USP9X anticorps
Aperçu rapide pour USP9X anticorps (ABIN7120533)
Antigène
Voir toutes USP9X AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- USP9X antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- ubiquitin specific peptidase 9, X-linked
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:5000, IF: 1:10-1:100, IHC: 1:20-1:200, IP: 1:200-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
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Autre désignation
- USP9X
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Sujet
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Synonyms: Probable ubiquitin carboxyl-terminal hydrolase FAF-X|Deubiquitinating enzyme FAF-X|Fat facets in mammals (hFAM)|Fat facets protein-related, X-linked|Ubiquitin thioesterase FAF-X|Ubiquitin-specific protease 9, X chromosome|Ubiquitin-specific-processing protease FAF-X|USP9X|DFFRX|FAM|USP9
Background: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
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Poids moléculaire
- 260-290 kDa
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ID gène
- 8239
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UniProt
- Q93008
Antigène
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