Ube2t anticorps

N° du produit ABIN7120563

Cet anticorps anti-Ube2t est un anticorps Lapin Polyclonal détectant Ube2t dans WB, ELISA et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Ube2t anticorps (ABIN7120563)

Antigène: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ube2t est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-Ube2t anticorps

Fonction: UBE2T antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin-conjugating enzyme E2T(putative)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Ube2t

Antigène: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Autre désignation: UBE2T

Sujet:

Synonyms: Ubiquitin-conjugating enzyme E2 T|Cell proliferation-inducing gene 50 protein|E2 ubiquitin-conjugating enzyme T|Ubiquitin carrier protein T|Ubiquitin-protein ligase T|UBE2T

Background: The ubiquitin(Ub)-mediated protein degradation pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub to specific protein substrates. The first step requires ATP-dependent activation of the C-terminus of Ub and the assembly of multi-Ubs by Ub-activating enzyme E1. The ubiquitin-conjugating enzyme E2, catalytic(UBCc) domain, is then conjugated to Ubs, through a thiol-ester linkage between a conserved cysteine and the C-terminus of Ub, to generate an intermediate Ub-E2 complex. Then the E3, a ligase, catalyzes the transfer of Ub from E2 to the appropriate substrate. This pathway regulates many fundamental cellular processes. There are also other E2s which form thiol-ester linkages without the use of E3s as well as several UBC homologs(TSG101, Mms2, Croc-1 and similar proteins), which lack the active site cysteine essential for ubiquitination and appear to function in DNA repair pathways.

Poids moléculaire: 24 kDa

ID gène: 28089

UniProt: Q9NPD8

Pathways: Chromatin Binding