UXT anticorps (AA 1-157)

N° du produit ABIN7120577

L’anticorps Lapin Polyclonal anti-UXT a été validé pour WB et ELISA. Il convient pour détecter UXT dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour UXT anticorps (AA 1-157) (ABIN7120577)

Antigène: UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UXT est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UXT anticorps

Épitope: AA 1-157

Fonction: UXT antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-157aa

Immunogen: ubiquitously-expressed transcript

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur UXT

Antigène: UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

Autre désignation: UXT

Sujet:

Synonyms: Protein UXT|Androgen receptor trapped clone 27 protein (ART-27)|Ubiquitously expressed transcript protein|UXT

Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription(AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation(PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling(PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC(PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function(PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM(PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.

Poids moléculaire: 18 kDa

ID gène: 8409

UniProt: Q9UBK9

Pathways: Unfolded Protein Response