UPF3B anticorps

N° du produit ABIN7120629

Cet anticorps anti-UPF3B est un anticorps Lapin Polyclonal détectant UPF3B dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour UPF3B anticorps (ABIN7120629)

Antigène: UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UPF3B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-UPF3B anticorps

Fonction: UPF3B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: UPF3 regulator of nonsense transcripts homolog B(yeast)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC:1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur UPF3B

Antigène: UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))

Autre désignation: UPF3B

Sujet:

Synonyms: Regulator of nonsense transcripts 3B|Nonsense mRNA reducing factor 3B|Up-frameshift suppressor 3 homolog B (hUpf3B)|Up-frameshift suppressor 3 homolog on chromosome X (hUpf3p-X)|UPF3B|RENT3B|UPF3X

Background: Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation, the function is independent of association with UPF2 and components of the EJC core.

Poids moléculaire: 58 kDa

ID gène: 65109

UniProt: Q9BZI7