UVRAG anticorps
Aperçu rapide pour UVRAG anticorps (ABIN7120667)
Antigène
Voir toutes UVRAG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- UVRAG antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- UV radiation resistance associated gene
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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Autre désignation
- UVRAG
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Sujet
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Synonyms: UV radiation resistance-associated gene protein|p63|UVRAG
Background: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
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Poids moléculaire
- 100 kDa
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ID gène
- 7405
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UniProt
- Q9P2Y5
Antigène
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