VAMP8 anticorps (AA 1-75)

N° du produit ABIN7120762

Cet anticorps Lapin Polyclonal détecte spécifiquement VAMP8 dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour VAMP8 anticorps (AA 1-75) (ABIN7120762)

Antigène: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAMP8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-VAMP8 anticorps

Épitope: AA 1-75

Fonction: VAMP8 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-75aa

Immunogen: vesicle-associated membrane protein 8(endobrevin)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur VAMP8

Antigène: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Autre désignation: VAMP8

Sujet:

Synonyms: Vesicle-associated membrane protein 8 (VAMP-8)|Endobrevin (EDB)|VAMP8

Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).

Poids moléculaire: 15 kDa

ID gène: 8673

UniProt: Q9BV40