YTHDC2 anticorps (AA 1131-1430)
Aperçu rapide pour YTHDC2 anticorps (AA 1131-1430) (ABIN7120902)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1131-1430
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Fonction
- YTHDC2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 1131-1430aa
Immunogen: 3'-5' RNA helicase YTHDC2
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IF: 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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Autre désignation
- YTHDC2
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Sujet
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Synonyms: 3'-5' RNA helicase YTHDC2|YTH domain-containing protein 2 (hYTHDC2)|YTHDC2
Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
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Poids moléculaire
- 160 kDa
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ID gène
- 64848
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UniProt
- Q9H6S0
Antigène
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