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YTHDC2 anticorps (AA 1131-1430)

Cet anticorps anti-YTHDC2 est un anticorps Lapin Polyclonal détectant YTHDC2 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7120902

Aperçu rapide pour YTHDC2 anticorps (AA 1131-1430) (ABIN7120902)

Antigène

YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Reactivité

  • 8
  • 2
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 9
Lapin

Clonalité

  • 6
  • 3
Polyclonal

Conjugué

  • 9
Cet anticorp YTHDC2 est non-conjugé

Application

  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • Épitope

    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1131-1430

    Fonction

    YTHDC2 antibody

    Purification

    Immunogen affinity purified

    Pureté

    ≥95 % as determined by SDS-PAGE

    Immunogène

    Immunogen sequence: 1131-1430aa

    Immunogen: 3'-5' RNA helicase YTHDC2

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:2000, IF: 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze / thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    -20°C for 12 months

    Date de péremption

    12 months
  • Antigène

    YTHDC2 (YTH Domain Containing 2 (YTHDC2))

    Autre désignation

    YTHDC2

    Sujet

    Synonyms: 3'-5' RNA helicase YTHDC2|YTH domain-containing protein 2 (hYTHDC2)|YTHDC2

    Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.

    Poids moléculaire

    160 kDa

    ID gène

    64848

    UniProt

    Q9H6S0
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