YTHDC2 anticorps (AA 1131-1430)

N° du produit ABIN7271425

Détail du produit anti-YTHDC2 anticorps

Antigène: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Épitope: AA 1131-1430

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YTHDC2 est non-conjugé

Application: Western Blotting (WB)

Fonction: YTHDC2 Rabbit pAb

Séquence: HSLFLRRMRA PSKPWSQVDE ATIRAIIAVL STEEQSAGLQ QPSGIGQRPR PMSSEELPLA SSWRSNNSRK SSADTEFSDE CTTAERVLMK SPSPALHPPQ KYKDRGILHP KRGTEDRSDQ SSLKSTDSSS YPSPCASPSP PSSGKGSKSP SPRPNMPVRY FIMKSSNLRN LEISQQKGIW STTPSNERKL NRAFWESSIV YLVFSVQGSG HFQGFSRMSS EIGREKSQDW GSAGLGGVFK VEWIRKESLP FQFAHHLLNP WNDNKKVQIS RDGQELEPLV GEQLLQLWER LPLGEKNTTD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1131-1430 of human YTHDC2 (NP_073739.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur YTHDC2

Antigène: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Autre désignation: YTHDC2 (YTHDC2 Produits)

Synonymes: anticorps 3010002F02Rik, anticorps BC037178, anticorps CAHL, anticorps YTH domain containing 2, anticorps Ythdc2, anticorps YTHDC2

Sujet: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016],YTHDC2;CAHL,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,YTHDC2

Poids moléculaire: 160kDa

ID gène: 64848

UniProt: Q9H6S0