CD55 anticorps (AA 1-100)

N° du produit ABIN7126277

Cet anticorps Souris Monoclonal détecte spécifiquement CD55 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CD55 anticorps (AA 1-100) (ABIN7126277)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD55 anticorps

Épitope: AA 1-100

Specificité: Recognizes a single chain glycoprotein of 70 kDa, identified as CD55/DAF. It is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 may be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa1-100) of human CD55 (exact sequence is proprietary)

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells or human lymphocytes. Human lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55

Sujet: CD55, CD55 Cromer blood group system, Complement decay-accelerating factor, CROM, DAF, GPI-DAF, Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form,CD55 / Decay Accelerating Factor (DAF)
Cellular localisation: Cell Surface. Secreted.

Poids moléculaire: 70kDa

ID gène: 1604, 126517

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity