PHKG2 anticorps (AA 81-180) (Biotin)

N° du produit ABIN708328

Cet anticorps Lapin Polyclonal détecte spécifiquement PHKG2 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour PHKG2 anticorps (AA 81-180) (Biotin) (ABIN708328)

Antigène: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHKG2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PHKG2 anticorps (Biotin)

Épitope: AA 81-180

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PHKG2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PHKG2

Antigène: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Autre désignation: PHKG2

Sujet:

Synonyms: GSD9C, PHK gamma LT, PHK gamma T, Phosphorylase b kinase gamma catalytic chain testis/liver isoform, Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, Phosphorylase kinase gamma subunit 2, Phosphorylase kinase subunit gamma 2, Phosphorylase kinase, gamma 2 testis, PHKG2_HUMAN, Phosphorylase kinase, gamma 2 testis/liver, PSK C3, Serine/threonine protein kinase PHKG2.

Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

ID gène: 5261

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process