Reelin anticorps (AA 1796-2115)

N° du produit ABIN7126322

Cet anticorps Souris Monoclonal détecte spécifiquement Reelin dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rongeurs.

Aperçu rapide pour Reelin anticorps (AA 1796-2115) (ABIN7126322)

Antigène: Reelin (RELN)

Reactivité: Humain, Souris, Rongeurs

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reelin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: RELN-4498

Détail du produit anti-Reelin anticorps

Épitope: AA 1796-2115

Fonction: Reelin Antibody

Specificité: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

Réactivité croisée (Details): Human, Mouse and Rodent.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 1796-2115) of human RELN protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human or mouse brain or CNS.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Reelin

Antigène: Reelin (RELN)

Autre désignation: RELN

Sujet:

LIS2, PRO1598, Reeler, Reelin, RELN, RELN_HUMAN, RL

Human or mouse brain or CNS.

Poids moléculaire: 387.5kDa

ID gène: 19699, 655654

UniProt: P78509

Pathways: Synaptic Membrane