Recombinant ALDH1A1 anticorps (AA 315-434)

N° du produit ABIN7126364

Cet anticorps Lapin Monoclonal détecte spécifiquement ALDH1A1 dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant ALDH1A1 anticorps (AA 315-434) (ABIN7126364)

Antigène: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ALDH1A1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-ALDH1A1 anticorps

Épitope: AA 315-434

Specificité: ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa 315-434) of human ALDH1A1 protein (exact sequence is proprietary).

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: K562, HepG2 or A549 cells. Human colon or testicular carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ALDH1A1

Antigène: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Autre désignation: ALDH1A1

Sujet: AHD2, ALDC, Aldehyde dehydrogenase 1 soluble, ALDH-E1, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li53e, HEL-S-53e, PUMB1, RALDH1, Retinal dehydrogenase 1,ALDH1A1 (Aldehyde Dehydrogenase 1A1)
Cellular localisation: Cytoplasm

Poids moléculaire: 56kDa

ID gène: 216, 76392

UniProt: P00352

Pathways: Dopaminergic Neurogenesis