FABP4 anticorps (AA 1-132)

N° du produit ABIN7126370

Cet anticorps Souris Monoclonal détecte spécifiquement FABP4 dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour FABP4 anticorps (AA 1-132) (ABIN7126370)

Antigène: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP4 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-FABP4 anticorps

Épitope: AA 1-132

Specificité: Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1 % of the total cytosolic protein in human adipose tissue.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa1-132) of human FABP4protein (exact sequence is proprietary)

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human adipose tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur FABP4

Antigène: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Autre désignation: FABP4

Sujet: 3T3-L1 lipid-binding protein, 422/aP2, A-FABP, Adipocyte lipid binding protein, Adipocyte protein AP2, Adipocyte-type fatty acid-binding protein, AFABP, ALBP/Ap2, aP2, Epididymis secretory protein Li 104, Fatty acid binding protein 4 adipocyte, HEL S 104, Lbpl, Myelin P2 protein homolog, P15, P2 adipocyte protein, Protein 422,Fatty Acid Binding Protein 4 (FABP4)
Cellular localisation: Cytoplasm. Nucleus.

Poids moléculaire: 15kDa

ID gène: 2167, 391561

UniProt: P15090

Pathways: Brown Fat Cell Differentiation