ZHX3 anticorps

N° du produit ABIN7126398

Détail du produit anti-ZHX3 anticorps

Antigène: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZHX3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human ZHX3 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human kidney, brain or thyroid.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ZHX3

Antigène: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Autre désignation: ZHX3 (ZHX3 Produits)

Synonymes: anticorps tix1, anticorps zgc:110489, anticorps TIX1, anticorps 1810059C13Rik, anticorps 4932418O04Rik, anticorps 9530010N21Rik, anticorps Tix1, anticorps mKIAA0395, anticorps zinc fingers and homeoboxes 3, anticorps zhx3, anticorps ZHX3, anticorps Zhx3

Sujet: KIAA0395, TIX1, Triple homeobox protein 1, ZHX 3, Zhx3, Zinc finger and homeodomain protein 3, Zinc fingers and homeoboxes protein 3,ZHX3 (Transcriptional Repressor)
Cellular localisation: Nucleus.

Poids moléculaire: 105kDa

ID gène: 23051, 380133

UniProt: Q9H4I2