Recombinant AKR1B1 anticorps
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- Antigène Voir toutes AKR1B1 Anticorps
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp AKR1B1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant human full-length AKR1B1 protein
- Isotype
- IgG
- Top Product
- Discover our top product AKR1B1 Anticorps primaire
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- Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: MOLT4, Jurkat or Raji cells. Human kidney or colon carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
- Autre désignation
- AKR1B1 (AKR1B1 Produits)
- Synonymes
- anticorps ADR, anticorps ALDR1, anticorps ALR2, anticorps AR, anticorps ALDRED, anticorps ALR-P-I, anticorps Akr1b3, anticorps Akr1b4, anticorps Aldr1, anticorps Alr, anticorps RATALDRED, anticorps akr1b7, anticorps zgc:86611, anticorps aldo-keto reductase family 1 member B, anticorps aldo-keto reductase family 1, member B1 (aldose reductase), anticorps aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog, anticorps AKR1B1, anticorps Akr1b1, anticorps akr1b1.S, anticorps akr1b1
- Sujet
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AKR1B1, Aldehyde reductase, aldehyde reductase 1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), Aldose reductase, AR, Lii5-2 CTCL tumor antigen, low Km aldose reductase,Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker)
Cellular localisation: Cytoplasm - Poids moléculaire
- 37kDa
- ID gène
- 231, 521212
- UniProt
- P15121
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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