SIRT3 anticorps

N° du produit ABIN7126428

L’anticorps Souris Monoclonal anti-SIRT3 a été validé pour WB, ELISA, IP, IF, FACS et Coat. Il convient pour détecter SIRT3 dans des échantillons de Humain.

Aperçu rapide pour SIRT3 anticorps (ABIN7126428)

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Détail du produit anti-SIRT3 anticorps

Specificité: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human SIRT3 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: SIRT3

Sujet: HSIRT3, Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase, NAD dependent deacetylase sirtuin 3 mitochondrial, Regulatory protein SIR2 homolog 3, SIR2 like protein 3, SIR2-like protein 3, SIR2L3, Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae), Sirtuin type 3, Sirtuin3,Sirtuin 3 (SIRT3)
Cellular localisation: Mitochondrion matrix.

Poids moléculaire: 43.57kDa

ID gène: 23410, 716456

UniProt: Q9NTG7