SIRT3 anticorps

N° du produit ABIN7126428

L’anticorps anti-SIRT3 Monoclonal Souris est utilisé pour la détection de SIRT3 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour SIRT3 anticorps (ABIN7126428)

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-SIRT3-1C10

Détail du produit anti-SIRT3 anticorps

Fonction: Sirtuin 3 (SIRT3) Antibody

Specificité: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human SIRT3 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: SIRT3

Sujet:

hSIRT3, Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase, NAD dependent deacetylase sirtuin 3 mitochondrial, Regulatory protein SIR2 homolog 3, SIR2 like protein 3, SIR2-like protein 3, SIR2L3, Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae), Sirtuin type 3, Sirtuin3

HeLa cells.

Poids moléculaire: 43.57kDa

ID gène: 23410, 716456

UniProt: Q9NTG7