Recombinant FOXP1 anticorps (AA 350-450)

N° du produit ABIN7126477

Cet anticorps anti-FOXP1 est un anticorps Lapin Monoclonal détectant FOXP1 dans IHC (f). Adapté pour Humain.

Aperçu rapide pour Recombinant FOXP1 anticorps (AA 350-450) (ABIN7126477)

Antigène: FOXP1 (Forkhead Box P1 (FOXP1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXP1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-FOXP1 anticorps

Épitope: AA 350-450

Specificité: Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( 80 % ) for FOXP1 is needed to achieve high specificity for the ABC subtype.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa350-450) of human FOXP1 protein (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human tonsil or colon.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur FOXP1

Antigène: FOXP1 (Forkhead Box P1 (FOXP1))

Autre désignation: FOXP1

Sujet: Fork head related protein like B, Forkhead box protein P1 (FOXP1), Glutamine rich factor 1, hFKH1B, HSPC215, QRF1,FOXP1 (Transcription Factor)
Cellular localisation: Nucleus.

Poids moléculaire: 75kDa

ID gène: 27086

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response