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Recombinant Prostate Specific Antigen anticorps

Cet anticorps anti-Prostate Specific Antigen est un anticorps Souris Monoclonal détectant Prostate Specific Antigen dans IHC (f). Adapté pour Humain.
N° du produit ABIN7126555

Aperçu rapide pour Recombinant Prostate Specific Antigen anticorps (ABIN7126555)

Antigène

Voir toutes Prostate Specific Antigen (PSA) Anticorps
Prostate Specific Antigen (PSA)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 190
  • 14
  • 13
  • 7
  • 1
  • 1
  • 1
Humain

Hôte

  • 105
  • 83
  • 4
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Souris

Clonalité

  • 128
  • 70
Monoclonal

Conjugué

  • 120
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  • 1
Cet anticorp Prostate Specific Antigen est non-conjugé

Application

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  • 68
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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Specificité

    Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant full-length human KLK3 (PSA) protein

    Isotype

    IgG2a
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: PC12 cells. Normal prostate or prostate carcinoma tissues.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    Prostate Specific Antigen (PSA)

    Autre désignation

    KLK3

    Sujet

    Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin,Prostate Specific Antigen (PSA)
    Cellular localisation: Cytoplasmic

    Poids moléculaire

    33-34kDa

    ID gène

    354, 171995

    UniProt

    P07288

    Pathways

    Système du Complément
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