LMYC anticorps
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- Antigène Voir toutes LMYC (MYCL) Anticorps
- LMYC (MYCL) (Protein L-Myc (MYCL))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LMYC est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Specificité
- Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human MYCL protein
- Isotype
- IgG2b
- Top Product
- Discover our top product MYCL Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Human small cell lung carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- LMYC (MYCL) (Protein L-Myc (MYCL))
- Autre désignation
- MYCL (MYCL Produits)
- Synonymes
- anticorps MRTL, anticorps MYCC, anticorps bHLHe39, anticorps c-Myc, anticorps MYCL1, anticorps Lmyc1, anticorps Mycl1, anticorps LMYC, anticorps bHLHe38, anticorps CMYC, anticorps c-myc, anticorps ARC, anticorps B430311C09Rik, anticorps MYC, anticorps NOP, anticorps Nop30, anticorps RNCMYC, anticorps mMyc, anticorps C-MYC, anticorps AU016757, anticorps Myc2, anticorps Niard, anticorps Nird, anticorps AW536278, anticorps L-myc, anticorps Lmyc-1, anticorps l-myc, anticorps lmyc, anticorps lmyc-b, anticorps lmyc2, anticorps mycl1-b, anticorps xL-Myc2, anticorps fi04c04, anticorps mycl1b, anticorps si:ch211-194e15.2, anticorps wu:fa07c04, anticorps wu:fb19f03, anticorps wu:fi04c04, anticorps zgc:152988, anticorps lmyc1, anticorps mycl1, anticorps mycl1a, anticorps zgc:85967, anticorps lmyc-A, anticorps mycl, anticorps mycl1-a, anticorps xL-Myc1, anticorps xL-myc1, anticorps MYC proto-oncogene, bHLH transcription factor, anticorps v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog, anticorps MYCL proto-oncogene, bHLH transcription factor, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps myelocytomatosis oncogene, anticorps v-myc avian myelocytomatosis viral oncogene lung carcinoma derived, anticorps MYCL proto-oncogene, bHLH transcription factor S homeolog, anticorps MYCL proto-oncogene, bHLH transcription factor b, anticorps MYCL proto-oncogene, bHLH transcription factor a, anticorps MYCL proto-oncogene, bHLH transcription factor L homeolog, anticorps MYC, anticorps MYCL, anticorps Mycl, anticorps Nol3, anticorps Myc, anticorps mycl.S, anticorps myclb, anticorps mycla, anticorps mycl.L
- Sujet
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BHLHe38, Class E basic helix-loop-helix protein 38, l myc 1 proto-oncogene, Myc related gene from lung cancer, oncogene lmyc, Protein L-Myc-1, v myc avian myelocytomatosis viral oncogene homolog 1 lung carcinoma derived,L-Myc / MYCL1 (Transcription Factor)
Cellular localisation: Nucleus. Nucleoplasm. Mitotic chromosome. - Poids moléculaire
- 40.33kDa
- ID gène
- 4610, 437922
- UniProt
- P12524
- Pathways
- L'effet Warburg
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