ZBTB7B anticorps
Aperçu rapide pour ZBTB7B anticorps (ABIN7126763)
Antigène
Voir toutes ZBTB7B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Th-Pok / ZBTB7B Antibody
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Specificité
- TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.
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Réactivité croisée (Details)
- Human.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human ZBTB7B protein
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Isotype
- IgG2b
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Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))
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Autre désignation
- ZBTB7B
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Sujet
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cKrox, hcKrox, T helper inducing POZ/Kruppel like factor, Th-POK, ThPOK, ZBTB15, ZBTB7B, ZFP67, Zinc finger and BTB domain containing 15, Zinc finger and BTB domain containing 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein ThPOK, ZNF857B
HeLa or HepG2 cells.
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Poids moléculaire
- 58/80kDa
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ID gène
- 51043, 729279
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UniProt
- O15156
Antigène
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