Recombinant S100P anticorps (C-Term)

N° du produit ABIN7126919

Cet anticorps anti-S100P Monoclonal Lapin (Clone S100P-4386R) (ABIN7126919) détecte spécifiquement S100P dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant S100P anticorps (C-Term) (ABIN7126919)

Antigène: S100P (S100 Calcium Binding Protein P (S100P))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp S100P est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: S100P-4386R

Détail du produit anti-S100P anticorps

Épitope: C-Term

Fonction: Recombinant S100P Antibody

Specificité: S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogène: Recombinant fragment corresponding to C-terminal of human S100P protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human pancreatic adenocarcinoma, placenta or spleen tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur S100P

Antigène: S100P (S100 Calcium Binding Protein P (S100P))

Autre désignation: S100P

Sujet:

Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P

Human pancreatic adenocarcinoma, placenta or spleen tissue.

Poids moléculaire: 10kDa

ID gène: 6286, 2962

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins