Recombinant Syndecan 1 anticorps (AA 200-300)

N° du produit ABIN7126925

Détail du produit anti-Syndecan 1 anticorps

Antigène: Syndecan 1 (SDC1)

Type d'anticorp: Recombinant Antibody

Épitope: AA 200-300

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syndecan 1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa200-300) of human CD138 protein (exact sequence is proprietary)

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human tonsil or lymph node.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Syndecan 1

Antigène: Syndecan 1 (SDC1)

Autre désignation: SDC1 (SDC1 Produits)

Synonymes: anticorps CG10497, anticorps CT27296, anticorps Dmel\\CG10497, anticorps Dsyn, anticorps Syd, anticorps Syn, anticorps dSdc, anticorps l(2)10608, anticorps sdc, anticorps syd, anticorps syn, anticorps Syn1, anticorps cd138, anticorps synd1, anticorps xSyn1, anticorps syndecan1, anticorps Syndecan-1, anticorps XSyndecan-1, anticorps SDC1, anticorps CD138, anticorps SDC, anticorps SYND1, anticorps syndecan, anticorps AA408134, anticorps AA409076, anticorps Sstn, anticorps Synd, anticorps Synd1, anticorps syn-1, anticorps HSPG, anticorps SYNDECA, anticorps Syndecan, anticorps Syndecan, anticorps syndecan 1, anticorps Sdc, anticorps sdc1, anticorps SDC1, anticorps Sdc1

Sujet: Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor, SDC1, SYND1, Syndecan Proteoglycan 1, Syndecan-1,CD138 / Syndecan-1 (SDC1) (Plasma Cell Marker)
Cellular localisation: Cell Surface

Poids moléculaire: 85kDa

ID gène: 6382, 224607

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism