VCAM1 anticorps
Aperçu rapide pour VCAM1 anticorps (ABIN7127044)
Antigène
Voir toutes VCAM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant full-length human VCAM1 protein
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Isotype
- IgG1
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Indications d'application
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Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: Human placenta or tonsil
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Autre désignation
- VCAM1
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Sujet
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CD106, INCAM-100, L1CAM, Vascular Cell Adhesion Molecule 1 (VCAM1), Vascular cell adhesion protein 1,CD106 / VCAM1 (Activated Endothelial Cell Marker)
Cellular localisation: Cell surface -
Poids moléculaire
- 110kDa
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ID gène
- 7412, 109225
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UniProt
- P19320
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Pathways
- Carbohydrate Homeostasis
Antigène
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