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NOC4L anticorps

NOC4L Reactivité: Humain FACS, IF Hôte: Souris Monoclonal unconjugated
N° du produit ABIN7127072
  • Antigène Tous les produits NOC4L
    NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))
    Reactivité
    • 17
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 16
    • 1
    Souris
    Clonalité
    • 17
    Monoclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOC4L est non-conjugé
    Application
    • 10
    • 4
    • 3
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificité
    Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
    Réactivité croisée (Details)
    Human
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant full-length human NOC4L protein
    Isotype
    IgG1
  • Indications d'application

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or 293T cells.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))
    Autre désignation
    NOC4L (NOC4L Produits)
    Synonymes
    anticorps NET49, anticorps NOC4, anticorps UTP19, anticorps NOC4L, anticorps AI326906, anticorps RGD1310661, anticorps net49, anticorps noc4, anticorps noc4lb, anticorps noc4la, anticorps NOC4 protein homolog, anticorps sb:cb534, anticorps wu:fb78g04, anticorps zgc:110429, anticorps nucleolar complex associated 4 homolog, anticorps NOC4 like, anticorps nucleolar complex associated 4 homolog S homeolog, anticorps nucleolar complex associated 4 homolog L homeolog, anticorps NOC4L, anticorps Noc4l, anticorps noc4l.S, anticorps noc4l.L, anticorps noc4l
    Sujet
    NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein,Nucleolar complex-associated protein 4-like protein (NOC4L)
    Cellular localisation: Nucleus.
    Poids moléculaire
    58.4kDa
    ID gène
    79050, 558536
    UniProt
    Q9BVI4