NOC4L anticorps

N° du produit ABIN7127072

Cet anticorps anti-NOC4L Monoclonal Souris (Clone PCRP-NOC4L-1B2) (ABIN7127072) détecte spécifiquement NOC4L dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NOC4L anticorps (ABIN7127072)

Antigène: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOC4L est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-NOC4L-1B2

Détail du produit anti-NOC4L anticorps

Fonction: Nucleolar complex-associated protein 4-like protein (NOC4L) Antibody

Specificité: Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

Réactivité croisée (Details): Human

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human NOC4L protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or 293T cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NOC4L

Antigène: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Autre désignation: NOC4L

Sujet:

NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein

HeLa or 293T cells.

Poids moléculaire: 58.4kDa

ID gène: 79050, 558536

UniProt: Q9BVI4