NOC4L anticorps

N° du produit ABIN7863519

L’anticorps anti-NOC4L Monoclonal Souris est utilisé pour la détection de NOC4L dans des échantillons de Humain. Il a été validé pour FACS et IF.

Aperçu rapide pour NOC4L anticorps (ABIN7863519)

Antigène: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOC4L est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-NOC4L-1B2

Détail du produit anti-NOC4L anticorps

Fonction: Nucleolar complex-associated protein 4-like protein (NOC4L) Antibody

Specificité: Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human NOC4L protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NOC4L

Antigène: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Autre désignation: Nucleolar complex-associated protein 4-like protein

Sujet:

NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein

HeLa or 293T cells.

Poids moléculaire: 58.4kDa

ID gène: 79050, 558536

UniProt: Q9BVI4