Recombinant Keratin 77 anticorps (AA 100-200)

N° du produit ABIN7127251

L’anticorps Souris Monoclonal anti-Keratin 77 a été validé pour IHC (f). Il convient pour détecter Keratin 77 dans des échantillons de Humain.

Aperçu rapide pour Recombinant Keratin 77 anticorps (AA 100-200) (ABIN7127251)

Antigène: Keratin 77 (KRT77)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 77 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-Keratin 77 anticorps

Épitope: AA 100-200

Specificité: The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Synthetic peptide corresponding to Type I Cytokeratins residues within aa100-200 of Type I Cytokeratins

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Skin or squamous cell carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Keratin 77

Antigène: Keratin 77 (KRT77)

Autre désignation: KRT77

Sujet: K1B, KRT1B, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B,Cytokeratin, Type I (Epithelial Marker)
Cellular localisation: Cytoplasmic

Poids moléculaire: 60/53/51/45/40kDa

ID gène: 374454, 334989

UniProt: Q7Z794