Recombinant APOC3 anticorps

N° du produit ABIN7127343

L’anticorps Lapin Monoclonal anti-APOC3 a été validé pour ELISA et IHC. Il convient pour détecter APOC3 dans des échantillons de Humain.

Aperçu rapide pour Recombinant APOC3 anticorps (ABIN7127343)

Antigène: APOC3 (Apolipoprotein C-III (APOC3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp APOC3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 8H12

Détail du produit anti-APOC3 anticorps

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human APOC3

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur APOC3

Antigène: APOC3 (Apolipoprotein C-III (APOC3))

Autre désignation: APOC3

Sujet:

Background: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).

Aliases: Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3), APOC3

UniProt: P02656

Pathways: Carbohydrate Homeostasis, Lipid Metabolism