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Recombinant c-FOS anticorps

c-Fos Reactivité: Humain WB, ELISA, IHC, FACS, IF Hôte: Lapin Monoclonal 14C10 unconjugated Recombinant Antibody
N° du produit ABIN7127496
  • Antigène Voir toutes c-FOS (c-Fos) Anticorps
    c-FOS (c-Fos) (c-Fos)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 247
    • 155
    • 136
    • 13
    • 12
    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 200
    • 73
    • 8
    • 1
    Lapin
    Clonalité
    • 198
    • 83
    Monoclonal
    Conjugué
    • 112
    • 17
    • 15
    • 15
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    Cet anticorp c-FOS est non-conjugé
    Application
    • 241
    • 80
    • 80
    • 76
    • 63
    • 39
    • 34
    • 26
    • 13
    • 13
    • 11
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human FOS
    Clone
    14C10
    Isotype
    IgG
    Top Product
    Discover our top product c-Fos Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    c-FOS (c-Fos) (c-Fos)
    Autre désignation
    FOS (c-Fos Produits)
    Synonymes
    anticorps AP-1, anticorps C-FOS, anticorps p55, anticorps c-fos, anticorps D12Rfj1, anticorps cFos, anticorps cFOS, anticorps fos, anticorps Fos proto-oncogene, AP-1 transcription factor subunit, anticorps FBJ osteosarcoma oncogene, anticorps proto-oncogene c-Fos-like, anticorps FOS, anticorps Fos, anticorps LOC101078177
    Sujet

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Aliases: Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7

    UniProt
    P01100
    Pathways
    S100 Proteins
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