Recombinant ILK anticorps

N° du produit ABIN7127572

Cet anticorps anti-ILK est un anticorps Lapin Monoclonal détectant ILK dans WB, ELISA, IP et IF. Adapté pour Humain.

Aperçu rapide pour Recombinant ILK anticorps (ABIN7127572)

Antigène: ILK (Integrin-Linked Kinase (ILK))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ILK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: 6A5

Détail du produit anti-ILK anticorps

Fonction: ILK Recombinant Monoclonal Antibody

Réactivité croisée: Souris

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human ILK

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5000, IF:1:20-1:200, IP:1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ILK

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: ILK

Sujet:

Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).

Aliases: Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (ILK-1) (ILK-2) (p59ILK), ILK, ILK1 ILK2

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration