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Recombinant Menin anticorps

MEN1 Reactivité: Humain WB, ELISA Hôte: Lapin Monoclonal 8G11 unconjugated Recombinant Antibody
N° du produit ABIN7127614
  • Antigène Voir toutes Menin (MEN1) Anticorps
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 77
    • 32
    • 24
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 69
    • 6
    • 2
    • 1
    Lapin
    Clonalité
    • 71
    • 7
    Monoclonal
    Conjugué
    • 39
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Menin est non-conjugé
    Application
    • 57
    • 38
    • 23
    • 18
    • 13
    • 13
    • 11
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human Menin
    Clone
    8G11
    Isotype
    IgG
    Top Product
    Discover our top product MEN1 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Autre désignation
    MEN1 (MEN1 Produits)
    Synonymes
    anticorps MEAI, anticorps SCG2, anticorps menin, anticorps meai, anticorps scg2, anticorps AW045611, anticorps menin 1, anticorps menin 1 L homeolog, anticorps multiple endocrine neoplasia I, anticorps multiple endocrine neoplasia 1, anticorps MEN1, anticorps men1, anticorps men1.L, anticorps Men1
    Sujet

    Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

    Aliases: Menin, MEN1, SCG2

    UniProt
    O00255
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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