Recombinant SF3B1 anticorps

N° du produit ABIN7127805

L’anticorps Lapin Monoclonal anti-SF3B1 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter SF3B1 dans des échantillons de Humain.

Aperçu rapide pour Recombinant SF3B1 anticorps (ABIN7127805)

Antigène: SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SF3B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 6C7

Détail du produit anti-SF3B1 anticorps

Réactivité croisée: Humain, Souris

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human SF3B1

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SF3B1

Antigène: SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Autre désignation: SF3B1

Sujet:

Background: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Aliases: Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155), SF3B1, SAP155

UniProt: O75533

Pathways: Chromatin Binding