Recombinant SIRT5 anticorps
-
- Antigène Voir toutes SIRT5 Anticorps
- SIRT5 (Sirtuin 5 (SIRT5))
- Type d'anticorp
- Recombinant Antibody
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp SIRT5 est non-conjugé
-
Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Affinity-chromatography
- Immunogène
- A synthesized peptide derived from human SIRT5
- Clone
- 9H12
- Isotype
- IgG
- Top Product
- Discover our top product SIRT5 Anticorps primaire
-
-
- Indications d'application
- Recommended dilution: IHC:1:50-1:200,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- SIRT5 (Sirtuin 5 (SIRT5))
- Autre désignation
- SIRT5 (SIRT5 Produits)
- Synonymes
- anticorps SIR2L5, anticorps 0610012J09Rik, anticorps 1500032M05Rik, anticorps AV001953, anticorps zgc:92288, anticorps sirt5-a, anticorps SIRT5, anticorps sir2l5, anticorps sirtuin 5, anticorps sirtuin 5 L homeolog, anticorps SIRT5, anticorps Sirt5, anticorps sirt5, anticorps sirt5.L, anticorps CC1G_00083
- Sujet
-
Background: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
Aliases: NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5), SIRT5, SIR2L5
- UniProt
- Q9NXA8
- Pathways
- SARS-CoV-2 Protein Interactome
-