Recombinant MAPT anticorps

N° du produit ABIN7127835

L’anticorps anti-MAPT Monoclonal produit chez le Lapin a été validé pour ELISA et IHC. Il convient pour la détection de MAPT dans des échantillons provenant de Humain. }

Aperçu rapide pour Recombinant MAPT anticorps (ABIN7127835)

Antigène: MAPT (Microtubule-Associated Protein tau (MAPT))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MAPT est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 4A1

Détail du produit anti-MAPT anticorps

Fonction: MAPT Recombinant Monoclonal Antibody

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Tau

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MAPT

Antigène: MAPT (Microtubule-Associated Protein tau (MAPT))

Autre désignation: MAPT

Sujet:

Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Aliases: Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau), MAPT, MAPTL MTBT1 TAU

UniProt: P10636

Pathways: Signalisation MAPK, Dynamique des Microtubules, M Phase, Regulation of Cell Size