Recombinant TXN anticorps
Aperçu rapide pour Recombinant TXN anticorps (ABIN7127856)
Antigène
Voir toutes TXN AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- TXN Recombinant Monoclonal Antibody
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Réactivité croisée
- Rat
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human TRX1
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TXN (Thioredoxin (TXN))
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Autre désignation
- TXN
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Sujet
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Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Aliases: Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP), TXN, TRDX TRX TRX1
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UniProt
- P10599
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Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
Antigène
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