RASGEF1A anticorps
Aperçu rapide pour RASGEF1A anticorps (ABIN7130823)
Antigène
Voir toutes RASGEF1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RASGEF1A Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Fusion protein of Human RASGEF1A
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RASGEF1A (RasGEF Domain Family, Member 1A (RASGEF1A))
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Autre désignation
- RASGEF1A
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Sujet
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Background: RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
Aliases: CG4853 gene product antibody, Ras-GEF domain-containing family member 1A antibody, RasGEF domain family, member 1A antibody, rasgef1a antibody, RGF1A_HUMAN antibody
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UniProt
- Q8N9B8
Antigène
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