GRIPAP1 anticorps (AA 814-818)

N° du produit ABIN7138016

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIPAP1 dans WB et ELISA. Il présente une réactivité envers Rat.

Aperçu rapide pour GRIPAP1 anticorps (AA 814-818) (ABIN7138016)

Antigène: GRIPAP1 (GRIP1 Associated Protein 1 (GRIPAP1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIPAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GRIPAP1 anticorps

Épitope: AA 814-818

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide

Immunogène: Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRIPAP1

Antigène: GRIPAP1 (GRIP1 Associated Protein 1 (GRIPAP1))

Autre désignation: Gripap1

Sujet:

Background: GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid proteinencoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipperregion and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.

Kitano, J., Kimura, K., Yamazaki, Y., Soda, T., Shigemoto, R., Nakajima, Y.and Nakanishi, S. 2002. Tamalin, J. Neurosci. 22: 280-1289.
Hall, B.S., Gabernet-Castello, C., Voak, A., Goulding, D., Natesan, S.K. and Field, M.C. 2006. J. Biol. Chem. 281: 27600-27612.
Sugi, T., Oyama, T., Muto, T., Nakanishi, S., Morikawa, K. and Jingami, H. 2007. Crystal structures of autoinhibitory PDZ domain of Tamalin EMBO J.26: 2192-2205.

Aliases: Gripap1 antibody, Grasp1GRIP1-associated protein 1 antibody, GRASP-1) [Cleaved into: GRASP-1 C-terminal chain antibody, 30 kDa C-terminus form)] antibody

UniProt: Q9JHZ4

Pathways: SARS-CoV-2 Protein Interactome