Oncostatin M Receptor anticorps (Cy5)

N° du produit ABIN709620

Cet anticorps anti-Oncostatin M Receptor est un anticorps Lapin Polyclonal détectant Oncostatin M Receptor dans WB. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Oncostatin M Receptor anticorps (Cy5) (ABIN709620)

Antigène: Oncostatin M Receptor (OSMR)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oncostatin M Receptor est conjugé à/à la Cy5

Application: Western Blotting (WB)

Détail du produit anti-Oncostatin M Receptor anticorps (Cy5)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Oncostatin-M receptor

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Oncostatin M Receptor (Cy5) (ABIN709620)

Guo, Li, Gong, Xiang, Zhang, Zhao, Li, Zheng, Zhu, Lei, Minoru, Li: "Oncostatin M Confers Neuroprotection against Ischemic Stroke." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 34, pp. 12047-62, (2015) (PubMed).

Détails sur Oncostatin M Receptor

Antigène: Oncostatin M Receptor (OSMR)

Autre désignation: Osmr

Sujet:

Synonyms: Oncostatin M receptor, Oncostatin M specic receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, Oncostatin-M-specic receptor, beta, OSMRB, MGC140467, MGC150626, MGC150627, MGC75127.

Background: Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.

ID gène: 157869

Pathways: Signalistation JAK/STAT, Growth Factor Binding