CDC25B anticorps (pSer149)
-
- Antigène Voir toutes CDC25B Anticorps
- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
-
Épitope
- pSer149
-
Reactivité
- Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CDC25B est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Souris, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P) derived from Mouse Cdc25B.
- Isotype
- IgG
- Top Product
- Discover our top product CDC25B Anticorps primaire
-
-
- Indications d'application
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
- Autre désignation
- Cdc25b (CDC25B Produits)
- Synonymes
- anticorps CDC25B, anticorps AI604853, anticorps cell division cycle 25B, anticorps cdc25b, anticorps CDC25B, anticorps Cdc25b
- Sujet
-
Background:
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Li G, et al. (2010) Retrovirology.7:59.
Wang Z,et al. (2010) BMC Cancer.10:233.
Lucci MA,et al. (2010) Cell Oncol.32(5-6):361-72.Aliases: CDC25B
- UniProt
- Q9DBN8
- Pathways
- Cycle Cellulaire, M Phase, Autophagy
-