IGFBP3 anticorps (pSer183)

N° du produit ABIN7138457

Cet anticorps Lapin Polyclonal détecte spécifiquement IGFBP3 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour IGFBP3 anticorps (pSer183) (ABIN7138457)

Antigène: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IGFBP3 anticorps

Épitope: pSer183

Fonction: Phospho-IGFBP3 (Ser183) Antibody

Réactivité croisée: Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 183(K-D-S(p)-Q-R) derived from Human IGFBP-3 .

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IGFBP3

Antigène: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Autre désignation: IGFBP3

Sujet:

Background:

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 .

Aliases: Acid stable subunit of the 140 K IGF complex antibody, Binding protein 29 antibody, Binding protein 53 antibody, BP 53 antibody, BP53 antibody, Growth hormone dependent binding protein antibody, IBP 3 antibody, IBP-3 antibody, IBP3 antibody, IBP3_HUMAN antibody, IGF binding protein 3 antibody, IGF-binding protein 3 antibody, IGFBP 3 antibody, IGFBP-3 antibody, IGFBP3 antibody, Insulin Like Growth Factor Binding Protein 3 antibody, Insulin-like growth factor binding protein 3 precursor antibody, Insulin-like growth factor-binding protein 3 antibody

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding