Cytokeratin 18 anticorps (pSer33)

N° du produit ABIN7138559

Cet anticorps Lapin Polyclonal détecte spécifiquement Cytokeratin 18 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Cytokeratin 18 anticorps (pSer33) (ABIN7138559)

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytokeratin 18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Cytokeratin 18 anticorps

Épitope: pSer33

Fonction: Phospho-KRT18 (Ser33) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 33 (A-A-S(p)-V-Y) derived from Human Keratin 18 (CK18).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cytokeratin 18

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Autre désignation: KRT18

Sujet:

Background: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. utations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Ramaekers, F.C. and Bosman, F.T. (2004) J. Pathol. 204, 351-354.
Chang, L. and Goldman, R.D. (2004) Nat. Rev. Mol. Cell Biol. 5, 601-613.
Moll, R. et al. (1982) Cell 31, 11-24.

Aliases: Cell proliferation inducing gene 46 protein antibody, Cell proliferation inducing protein 46 antibody, Cell proliferation-inducing gene 46 protein antibody, CK 18 antibody, CK-18 antibody, CK18 antibody, CYK 18 antibody, CYK18 antibody, Cytokeratin 18 antibody, Cytokeratin endo B antibody, Cytokeratin-18 antibody, K 18 antibody, K18 antibody, K1C18_HUMAN antibody, KA18 antibody, Keratin 18 antibody, Keratin 18, type I antibody, Keratin D antibody, keratin, type I cytoskeletal 18 antibody, Keratin-18 antibody, Krt18 antibody

UniProt: P05783

Pathways: Apoptose, Caspase Cascade in Apoptosis