beta 2 Adrenergic Receptor anticorps (pSer346)

N° du produit ABIN7138567

Cet anticorps anti-beta 2 Adrenergic Receptor est un anticorps Lapin Polyclonal détectant beta 2 Adrenergic Receptor dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour beta 2 Adrenergic Receptor anticorps (pSer346) (ABIN7138567)

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta 2 Adrenergic Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-beta 2 Adrenergic Receptor anticorps

Épitope: pSer346

Fonction: Phospho-ADRB2 (Ser346) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur beta 2 Adrenergic Receptor

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Autre désignation: ADRB2

Sujet:

Background:

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3
24690384 Curated Info
Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94
Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40

Aliases: ADRB2 antibody, ADRB2_HUMAN antibody, ADRB2R antibody, ADRBR antibody, Adrenergic beta 2 receptor surface antibody, Adrenoceptor beta 2 surface antibody, B2AR antibody, BAR antibody, beta 2 adrenoceptor antibody, Beta 2 adrenoreceptor antibody, Beta-2 adrenergic receptor antibody, Beta-2 adrenoceptor antibody, Beta-2 adrenoreceptor antibody, BETA2AR antibody, Catecholamine receptor antibody, OTTHUMP00000160386 antibody

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation