CAMK2A anticorps (pThr286)

N° du produit ABIN7138826

Cet anticorps Lapin Polyclonal détecte spécifiquement CAMK2A dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CAMK2A anticorps (pThr286) (ABIN7138826)

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMK2A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CAMK2A anticorps

Épitope: pThr286

Fonction: Phospho-CAMK2A (Thr286) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of threonine 286 (Q-E-T(p)-V-D) derived from Human CaMKII.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CAMK2A

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Autre désignation: CAMK2A

Sujet:

Background:

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity

Pak JH, et al. Proc Natl Acad Sci U S A. 2000 Oct 10, 97(21): 11232-11237
Hudmon A, et al. J Cell Biol. Author manuscript, available in PMC 2006 May 7
Miller P, et al. PLoS Biol. 2005 Apr, 3(4): e107
Runyan JD, et al. Learn Mem. 2005 Mar, 12(2): 103-110.

Aliases: Calcium/calmodulin dependent protein kinase II alpha antibody, Calcium/calmodulin dependent protein kinase II beta antibody, Calcium/calmodulin dependent protein kinase II delta antibody, Calcium/calmodulin dependent protein kinase II gamma antibody, Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody, CaM kinase II alpha antibody, CaM kinase II antibody, CaM kinase II beta antibody, CaM kinase II delta antibody, CaM kinase II gamma antibody, CaM kinase II subunit alpha antibody, CaMK-II subunit alpha antibody, CAMK2 antibody, Camk2a antibody, CAMK2B antibody, CAMK2D antibody, CAMK2G antibody, CAMKA antibody, KCC2A_HUMAN antibody

UniProt: Q9UQM7

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction