CSNK2A1/CK II alpha anticorps (pSer362, pThr360)
Aperçu rapide pour CSNK2A1/CK II alpha anticorps (pSer362, pThr360) (ABIN7138896)
Antigène
Voir toutes CSNK2A1/CK II alpha (CSNK2A1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer362, pThr360
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Fonction
- Phospho-CSNK2A1 (Thr360/Ser362) Antibody
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Réactivité croisée
- Souris, Rat
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Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogène
- Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-T(p)-P-S(p)-P-L) derived from Human CK2a.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
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Autre désignation
- CSNK2A1
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Sujet
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Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001)
Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)
Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)
Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000)Aliases: Casein kinase 2 alpha 1 polypeptide antibody, Casein kinase II alpha 1 antibody, Casein kinase II alpha 1 subunit antibody, Casein kinase II alpha subunit antibody, Casein kinase II subunit alpha antibody, CK II alpha antibody, CK II antibody, CK2 alpha antibody, CK2 catalytic subunit alpha antibody, CK2A1 antibody, CKII antibody, CKIIalpha antibody, CSK21_HUMAN antibody, CSNK2A1 antibody
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UniProt
- P68400
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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