Ephrin B2 anticorps (pTyr316)

N° du produit ABIN7138977

L’anticorps Lapin Polyclonal anti-Ephrin B2 a été validé pour WB et ELISA. Il convient pour détecter Ephrin B2 dans des échantillons de Humain.

Aperçu rapide pour Ephrin B2 anticorps (pTyr316) (ABIN7138977)

Antigène: Ephrin B2 (EFNB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin B2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Ephrin B2 anticorps

Épitope: pTyr316

Fonction: Phospho-EFNB2 (Tyr316) Antibody

Réactivité croisée: Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Ephrin B2

Antigène: Ephrin B2 (EFNB2)

Autre désignation: EFNB2

Sujet:

Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Chrencik JE,et al.( 2006) J Biol Chem,281(38):28185-28192.
Kertesz N, et al.( 2006) Blood,107(6):2330-2338.
Noren NK, et al.( 2004) Proc Natl Acad Sci USA,101(15):5583-5588

Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody

UniProt: P52799

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation