HCLS1 anticorps (pTyr397)

N° du produit ABIN7138997

Cet anticorps Lapin Polyclonal détecte spécifiquement HCLS1 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour HCLS1 anticorps (pTyr397) (ABIN7138997)

Antigène: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCLS1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HCLS1 anticorps

Épitope: pTyr397

Fonction: Phospho-HCLS1 (Tyr397) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 .

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HCLS1

Antigène: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Autre désignation: HCLS1

Sujet:

Background:

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.

Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: Cortactin like antibody, CTTNL antibody, HCLS 1 antibody, Hcls1 antibody, HCLS1_HUMAN antibody, Hematopoietic cell specific Lyn substrate 1 antibody, Hematopoietic cell-specific LYN substrate 1 antibody, Hematopoietic lineage cell-specific protein antibody, HS 1 antibody, HS1 antibody, LckBP1 antibody, OTTHUMP00000215180 antibody, OTTHUMP00000215182 antibody, p75 antibody

UniProt: P14317

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Maintenance of Protein Location