EPH Receptor A7 anticorps (pTyr791)

N° du produit ABIN7139071

Cet anticorps anti-EPH Receptor A7 est un anticorps Lapin Polyclonal détectant EPH Receptor A7 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour EPH Receptor A7 anticorps (pTyr791) (ABIN7139071)

Antigène: EPH Receptor A7 (EPHA7)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EPH Receptor A7 anticorps

Épitope: pTyr791

Fonction: Phospho-EPHA7 (Tyr791) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y(p)-T-T) derived from Human EPHA7 .

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPH Receptor A7

Antigène: EPH Receptor A7 (EPHA7)

Autre désignation: EPHA7

Sujet:

Background:

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.

Fox G.M., Oncogene 10:897-905(1995).
Mungall A.J., Nature 425:805-811(2003).

Aliases: Cek 11 antibody, Developmental kinase 1 antibody, EBK antibody, EHK-3 antibody, EHK3 antibody, EK11 antibody, Embryonic brain kinase antibody, EPH homology kinase 3 antibody, EPH-like kinase 11 antibody, Epha7 antibody, EPHA7_HUMAN antibody, Ephrin receptor Eph A7 antibody, Ephrin type A receptor 7 antibody, Ephrin type-A receptor 7 antibody, hEK11 antibody, MDK 1 antibody, Receptor protein tyrosine kinase HEK 11 antibody, Tyrosine protein kinase receptor EHK 3 antibody

UniProt: Q15375

Pathways: Signalisation RTK