KRT17 anticorps (AA 1-441) (HRP)

N° du produit ABIN7140841

Cet anticorps anti-KRT17 est un anticorps Lapin Polyclonal détectant KRT17 dans ELISA. Adapté pour Boeuf (Vache).

Aperçu rapide pour KRT17 anticorps (AA 1-441) (HRP) (ABIN7140841)

Antigène: KRT17 (Keratin 17 (KRT17))

Reactivité: Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT17 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-KRT17 anticorps (HRP)

Épitope: AA 1-441

Fonction: KRT17 Antibody, HRP conjugated

Réactivité croisée: Boeuf (Vache)

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KRT17

Antigène: KRT17 (Keratin 17 (KRT17))

Autre désignation: KRT17

Sujet:

Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial \"stem cells\". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

Aliases: KRT17 antibody, Keratin antibody, type I cytoskeletal 17 antibody, Cytokeratin-17 antibody, CK-17 antibody, Keratin-17 antibody, K17 antibody

UniProt: A1L595