LC3B anticorps (AA 1-116)

N° du produit ABIN7140912

L’anticorps Lapin Polyclonal anti-LC3B a été validé pour ELISA. Il convient pour détecter LC3B dans des échantillons de Candida glabrata.

Aperçu rapide pour LC3B anticorps (AA 1-116) (ABIN7140912)

Antigène: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivité: Candida glabrata

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LC3B est non-conjugé

Application: ELISA

Détail du produit anti-LC3B anticorps

Épitope: AA 1-116

Fonction: ATG8 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Candida glabrata Autophagy-related protein 8 protein (1-116AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LC3B

Antigène: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Autre désignation: ATG8

Sujet:

Background: Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.

Aliases: ATG8 antibody, AUT7 antibody, CAGL0A04675gAutophagy-related protein 8 antibody, Autophagy-related ubiquitin-like modifier ATG8 antibody

UniProt: Q6FXR8

Pathways: Autophagy