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OAS3 anticorps (AA 424-565) (Biotin)

OAS3 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7142175
  • Antigène Voir toutes OAS3 Anticorps
    OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
    Épitope
    • 15
    • 8
    • 8
    • 4
    • 1
    • 1
    • 1
    AA 424-565
    Reactivité
    • 39
    • 16
    • 2
    Humain
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OAS3 est conjugé à/à la Biotin
    Application
    • 35
    • 20
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human 2\'-5\'-oligoadenylate synthase 3 protein (424-565AA)
    Isotype
    IgG
    Top Product
    Discover our top product OAS3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
    Autre désignation
    OAS3 (OAS3 Produits)
    Sujet

    Background: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2\'-5\'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV).

    Aliases: (2-5'')oligo(A) synthase 3 antibody, 2 5' oligo(A) synthetase 3 antibody, 2 5'LIGO antibody, 2 5A synthetase 3 antibody, 2''-5''-oligoadenylate synthase 3 antibody, 2-5A synthase 3 antibody, MGC133260 antibody, OAS3 2' 5' oligoadenylate synthetase 3, 100 kDa antibody, OAS3 antibody, OAS3_HUMAN antibody, p100 antibody, p100 OAS antibody, p100OAS antibody

    UniProt
    Q9Y6K5
    Pathways
    Hepatitis C
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